Education Technology

Life Science: Translation Mutation

by Texas Instruments - Simulation Lesson


  • Students will describe how a translation mutation can result in a genetic disease.
  • Students will describe how the substitution of one nucleic acid sequence results in the production of a faulty protein.



  • genotype
  • phenotype
  • gene
  • amino acid
  • protein
  • hemoglobin
  • mutation
  • sickle-cell anemia

About the Lesson

In this lesson, students will explore how gene mutations located on chromosomes result in harmful effects.

 As a result, students will:

  • Run a simulation that demonstrates each step:  nucleic acid substitution, amino acid substitution, protein shape, genetic disease.

 This activity was created using Lua. Learn more about Lua in TI-Nspire here.