In this lesson, students will explore how gene mutations that are located on chromosomes result in harmful effects.

• Students will describe how a translation mutation can result in a genetic disease.
• Students will describe how the substitution of one nucleic acid sequence results in the production of a faulty protein.

• genotype
• phenotype
• gene
• amino acid
• protein
• hemoglobin
• mutation
• sickle-cell anemia

In this lesson, students will explore how gene mutations located on chromosomes result in harmful effects.

 As a result, students will:

• Run a simulation that demonstrates each step:  nucleic acid substitution, amino acid substitution, protein shape, genetic disease.

 This activity was created using Lua. Learn more about Lua in TI-Nspire here.